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(7S)-2-(2-aminopyrimidin-4-yl)-7-(2-fluoroethyl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one
- Development stage
- Unknown
- Modality
- Small Molecules
01
Overview
This compound is a small molecule experimental drug belonging to the pyrrolopyridine class. It acts as an inhibitor of cell division cycle 7-related protein kinase (CDC7), a kinase involved in the initiation of DNA replication by phosphorylating substrates that regulate the G1/S phase transition such as MCM proteins and CLASPIN. The inhibition of CDC7 suggests potential applications in targeting proliferative diseases like cancer. The compound has been referenced under PubMed ID 19115845 and is identified by DrugBank accession DB07149. No marketed brand names or approved indications are currently available; it remains an experimental agent primarily studied for its kinase inhibitory activity.
- Other names
- (7S)-2-(2-amino-4-pyrimidinyl)-7-(2-fluoroethyl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one
02
Targets
CDC7 (Cell division cycle 7-related protein kinase)
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